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For Dark Spots
iS Clinical White Lightening Serum
*99 percent naturally derived
Many skin brighteners have an unwanted side effect: irritation. The natural extracts and acids in this serum soften spots with a gentle touch. Key Naturals: Extracts of Norwegian kelp, polyporus (a wild mushroom), and alpha-arbutin (a brightener) help prevent melanin from reaching the skin's surface, while naturally derived acids, including sugarcane extract (the source of glycolic acid), exfoliate to boost the effectiveness of the fading agents.
What It Doesn't Contain: Parabens, fragrance or synthetic preservatives.
The Results: When applied twice daily for 12 weeks, it lessened the intensity of pigmented areas by 75 percent. No one in the study reported irritation or sensitivity, and 84 percent had significant overall brightening.
What An Expert Says: "These extracts block the production and transport of pigment in a few ways," says Amy B. Lewis, a clinical assistant professor of dermatology at Yale Medical School. "The acids help buff away existing marks and brighten the skin."